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Tdark
ABHD14A
Protein ABHD14A

Protein Summary
Description
Possible role in granule neuron development.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000273596
  • ENSP00000273596
  • ENSG00000248487

Symbol
  • DORZ1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
disease perturbation
0.95
histone modification site profile
0.79
transcription factor perturbation
0.68
gene perturbation
0.65
tissue
0.61


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.92   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 120   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.92   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 120   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (55)
SLC39A12
Tbio
Family:  Transporter
Novelty:  0.09127395
p_int:  0.984870979
p_ni:  0.015125871
p_wrong:  0.00000315
Data Source:  BioPlex
IL13RA2
Tbio
Novelty:  0.03465642
p_int:  0.969797827
p_ni:  0.03020216
p_wrong:  1.3e-8
Data Source:  BioPlex
CEACAM21
Tdark
Novelty:  0.46116153
p_int:  0.961374736
p_ni:  0.038625217
p_wrong:  4.7e-8
Data Source:  BioPlex
SCARA3
Tbio
Novelty:  0.00621523
p_int:  0.949631709
p_ni:  0.050368291
Data Source:  BioPlex
CD1E
Tbio
Novelty:  0.00171622
p_int:  0.927536271
p_ni:  0.072463729
Data Source:  BioPlex
SLC39A5
Tbio
Family:  Transporter
Novelty:  0.05205571
p_int:  0.926359192
p_ni:  0.073640808
Data Source:  BioPlex
A4GALT
Tbio
Family:  Enzyme
Novelty:  0.00932062
p_int:  0.894867248
p_ni:  0.105122593
p_wrong:  0.000010159
Score:  0.252
Data Source:  BioPlex,STRINGDB
GGT7
Tbio
Family:  Enzyme
Novelty:  0.01374716
p_int:  0.880854649
p_ni:  0.119111568
p_wrong:  0.000033783
Score:  0.153
Data Source:  BioPlex,STRINGDB
TCTN2
Tbio
Novelty:  0.11617528
p_int:  0.87320657
p_ni:  0.126793412
p_wrong:  1.8e-8
Data Source:  BioPlex
CHRNB4
Tclin
Family:  IC
Novelty:  0.01151716
p_int:  0.872444896
p_ni:  0.098491678
p_wrong:  0.029063426
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (3)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Disease Associations (null)
No disease associations found
GWAS Traits (8)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
IGF-1 measurement
1
1
1
69.4
macrophage inflammatory protein 1b measurement
1
1
1
33.1
urate measurement
1
1
1
12.2
high density lipoprotein cholesterol measurement
1
1
1
10.6
apolipoprotein A 1 measurement
1
1
1
8.2
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
IGF-1 measurement
1
69.4
macrophage inflammatory protein 1b measurement
1
33.1
urate measurement
1
12.2
high density lipoprotein cholesterol measurement
1
10.6
apolipoprotein A 1 measurement
1
8.2
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (8)
1 – 5 of 8
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Mouse
MGI:1915894
68644
Rat
RGD:1309721
300982
Dog
abhydrolase domain containing 14A
VGNC:37461
484743
Horse
abhydrolase domain containing 14A
VGNC:14939
100629427
Pig
abhydrolase domain containing 14A
100625665
Species
Name
OMA
EggNOG
Inparanoid
Mouse
Rat
Dog
abhydrolase domain containing 14A
Horse
abhydrolase domain containing 14A
Pig
abhydrolase domain containing 14A
Publication Statistics
PubMed Score 0.92
PubMed score by year
PubTator Score 0.09
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title