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Tbio
ABHD11
Protein ABHD11

Protein Summary
Description
This gene encodes a protein containing an alpha/beta hydrolase fold domain. This gene is deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.23. [provided by RefSeq, Mar 2016]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000222800
  • ENSP00000222800
  • ENSG00000106077
  • ENST00000357419
  • ENSP00000392945
  • ENST00000395147
  • ENSP00000378579
  • ENST00000437775
  • ENSP00000416970

Symbol
  • WBSCR21
  • PP1226
  • WBSCR21
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor binding site profile
0.9
histone modification site profile
0.85
kinase perturbation
0.71
transcription factor
0.63
cell type or tissue
0.61


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 12.15   (req: < 5)
Gene RIFs: 4   (req: <= 3)
Antibodies: 115   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 12.15   (req: >= 5)
Gene RIFs: 4   (req: > 3)
Antibodies: 115   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (50)
OSTM1
Tbio
Novelty:  0.03033192
p_int:  0.999408261
p_ni:  0.000155982
p_wrong:  0.000435756
Data Source:  BioPlex
FAS
Tbio
Novelty:  0.00043286
p_int:  0.800220799
p_ni:  0.000112545
p_wrong:  0.199666657
Score:  0.345
Data Source:  BioPlex,STRINGDB
MAK16
Tdark
Novelty:  0.07717917
Score:  0.722
Data Source:  STRINGDB
TWISTNB
Tdark
Family:  Enzyme
Novelty:  0.59160737
Score:  0.719
Data Source:  STRINGDB
PAFAH2
Tbio
Family:  Enzyme
Novelty:  0.19881779
Score:  0.693
Data Source:  STRINGDB
ABHD13
Tdark
Family:  Enzyme
Novelty:  2.01646617
Score:  0.665
Data Source:  STRINGDB
UTP11
Tbio
Novelty:  0.20711838
Score:  0.663
Data Source:  STRINGDB
ABHD6
Tchem
Family:  Enzyme
Novelty:  0.019314
Score:  0.633
Data Source:  STRINGDB
NCEH1
Tchem
Family:  Enzyme
Novelty:  0.01528589
Score:  0.625
Data Source:  STRINGDB
APEH
Tchem
Family:  Enzyme
Novelty:  0.00090837
Score:  0.586
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (2)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Disease Associations (null)
No disease associations found
GWAS Traits (18)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
triglyceride measurement
6
10
14
99.2
mean platelet volume
3
2
3
82.9
IGF-1 measurement
1
3
3
80.3
serum gamma-glutamyl transferase measurement
1
2
2
72.4
waist circumference
1
2
2
62
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
triglyceride measurement
14
99.2
mean platelet volume
3
82.9
IGF-1 measurement
3
80.3
serum gamma-glutamyl transferase measurement
2
72.4
waist circumference
2
62
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
abhydrolase domain containing 11
VGNC:13623
472412
Macaque
abhydrolase domain containing 11
720147
Mouse
MGI:1916008
68758
Rat
RGD:1304681
360831
Dog
abhydrolase domain containing 11
VGNC:37457
489803
Species
Name
OMA
EggNOG
Inparanoid
Chimp
abhydrolase domain containing 11
Macaque
abhydrolase domain containing 11
Mouse
Rat
Dog
abhydrolase domain containing 11
Publication Statistics
PubMed Score 12.15
PubMed score by year
PubTator Score 7.23
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title