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Tbio
ABCF2
ATP-binding cassette sub-family F member 2

Protein Summary
Description
This gene encodes a member of the ATP-binding cassette (ABC) transporter superfamily. ATP-binding cassette proteins transport various molecules across extra- and intracellular membranes. Alterations in this gene may be involved in cancer progression. Related pseudogenes have been identified on chromosomes 3 and 7. [provided by RefSeq, Mar 2019]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000287844
  • ENSP00000287844
  • ENSG00000033050

Symbol
  • ABC28
  • HUSSY18
  • HUSSY-18
  • EST133090
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
molecular function
0.91
transcription factor perturbation
0.88
transcription factor binding site profile
0.84
kinase perturbation
0.81
disease perturbation
0.79


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 20.08   (req: < 5)
Gene RIFs: 6   (req: <= 3)
Antibodies: 311   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 20.08   (req: >= 5)
Gene RIFs: 6   (req: > 3)
Antibodies: 311   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0