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Tdark
EFCAB9
EF-hand calcium-binding domain-containing protein 9

Protein Summary
Description
This gene encodes a protein with a C-terminal EF-hand calcium-binding domain similar to that found in penta-EF-hand (PEF) protein family members. The EF-hand is a helix-loop-helix structure with a canonical twelve-residue sequence that coordinates a calcium molecule with pentagonal bipyramidal symmetry. [provided by RefSeq, Jul 2017]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000398186
  • ENSP00000381247
  • ENSG00000214360
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
0.71
cellular component
0.64
PubMedID
0.42
chemical
0.41
protein complex
0.4


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 0   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 0   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Gene Ontology Terms (1)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
InterPro
Protein-Protein Interactions (8)
1 – 8 of 8
MYH10
Tbio
Novelty: 0.00811239
Score: 0.634
Data Source: STRINGDB
OBSCN
Tbio
Family: Kinase
Novelty: 0.01608231
Score: 0.601
Data Source: STRINGDB
SPEG
Tbio
Family: Kinase
Novelty: 0.00284678
Score: 0.601
Data Source: STRINGDB
ASPM
Tbio
Novelty: 0.00712035
Score: 0.461
Data Source: STRINGDB
PPP3CC
Tbio
Family: Enzyme
Novelty: 0.04180044
Score: 0.406
Data Source: STRINGDB
PPP3CB
Tbio
Family: Enzyme
Novelty: 0.02520885
Score: 0.406
Data Source: STRINGDB
PPP3CA
Tchem
Family: Enzyme
Novelty: 0.00238194
Score: 0.406
Data Source: STRINGDB
IQCG
Tbio
Novelty: 0.2173913
Score: 0.401
Data Source: STRINGDB
Publication Statistics
PubMed Score  0.00

PubMed score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer