You are using an outdated browser. Please upgrade your browser to improve your experience.

Tdark
FAM171A2
Protein FAM171A2

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000293443
  • ENSP00000293443
  • ENSG00000161682
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell line
0.64
microRNA
0.61
histone modification site profile
0.57
tissue
0.53
tissue sample
0.42


Related Tools
Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.85   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 26   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.85   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 26   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
platelet count
1
1
0
2.4
3.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
platelet count
0
2.4
3.4
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
family with sequence similarity 171 member A2
VGNC:9428
454729
Mouse
MGI:2448496
217219
Rat
RGD:1307966
100361389
Dog
family with sequence similarity 171 member A2
VGNC:40623
612752
Horse
family with sequence similarity 171 member A2
106782685
Species
Name
OMA
EggNOG
Inparanoid
Chimp
family with sequence similarity 171 member A2
Mouse
Rat
Dog
family with sequence similarity 171 member A2
Horse
family with sequence similarity 171 member A2
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-A8MVW0-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (1)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Protein-Protein Interactions (40)
1 – 10 of 40
PCDHGB1
Tdark
Novelty: 0.60440805
p_int: 0.999989811
p_ni: 0.000010091
p_wrong: 9.8e-8
Score: 0.178
Data Source: BioPlex,STRINGDB
FAM171B
Tdark
Novelty: 0.38456365
p_int: 0.999980057
p_ni: 0.000019941
p_wrong: 2e-9
Score: 0.2
Data Source: BioPlex,STRINGDB
P4HA3
Tbio
Family: Enzyme
Novelty: 0.03832564
p_int: 0.99997729
p_ni: 0.00002264
p_wrong: 7e-8
Data Source: BioPlex
EFNB2
Tbio
Novelty: 0.00255095
p_int: 0.999329508
p_ni: 0.000670469
p_wrong: 2.3e-8
Data Source: BioPlex
BTN2A1
Tbio
Novelty: 0.02259329
p_int: 0.999010225
p_ni: 0.000989771
p_wrong: 3e-9
Data Source: BioPlex
PRDX2
Tbio
Novelty: 0.00189751
p_int: 0.998650376
p_ni: 0.001349616
p_wrong: 8e-9
Data Source: BioPlex
NCR3LG1
Tbio
Novelty: 0.02681936
p_int: 0.99518693
p_ni: 0.004813006
p_wrong: 6.4e-8
Data Source: BioPlex
IL7R
Tbio
Novelty: 0.00107223
p_int: 0.992023672
p_ni: 0.007976322
p_wrong: 7e-9
Data Source: BioPlex
BTNL3
Tdark
Novelty: 0.27343899
p_int: 0.99145172
p_ni: 0.00854825
p_wrong: 3.1e-8
Score: 0.169
Data Source: BioPlex,STRINGDB
TMEM30B
Tbio
Novelty: 0.26735006
p_int: 0.990449074
p_ni: 0.009550892
p_wrong: 3.4e-8
Data Source: BioPlex
Publication Statistics
PubMed Score  0.85

PubMed score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer