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Tbio
VGLL3
Transcription cofactor vestigial-like protein 3

Protein Summary
Description
May act as a specific coactivator for the mammalian TEFs.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000383698
  • ENSP00000373199
  • ENSG00000206538
  • ENST00000398399
  • ENSP00000381436

Symbol
  • VGL3
  • VGL-3
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.89
microRNA
0.75
PubMedID
0.71
histone modification site profile
0.66
gene perturbation
0.61


Protein Classes
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 31.88   (req: < 5)
Gene RIFs: 5   (req: <= 3)
Antibodies: 72   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 31.88   (req: >= 5)
Gene RIFs: 5   (req: > 3)
Antibodies: 72   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (37)
TEAD1
Tchem
Family:  TF
Novelty:  0.01198524
Score:  0.933
Data Source:  STRINGDB
WWTR1
Tbio
Novelty:  0.00431186
Score:  0.774
Data Source:  STRINGDB
CHMP2B
Tbio
Novelty:  0.01116381
Score:  0.755
Data Source:  STRINGDB
TEAD4
Tchem
Family:  TF
Novelty:  0.0114979
Score:  0.686
Data Source:  STRINGDB
YAP1
Tchem
Novelty:  0.00124225
Score:  0.672
Data Source:  STRINGDB
VGLL4
Tbio
Novelty:  0.03384856
Score:  0.662
Data Source:  STRINGDB
AKAP11
Tbio
Family:  Enzyme
Novelty:  0.0685826
Score:  0.653
Data Source:  STRINGDB
TEAD3
Tbio
Family:  TF
Novelty:  0.04014337
Score:  0.624
Data Source:  STRINGDB
SYT17
Tbio
Novelty:  0.03921503
Score:  0.618
Data Source:  STRINGDB
POU1F1
Tbio
Family:  TF
Novelty:  0.0052029
Score:  0.555
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (2)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Disease Associations ()
No disease associations found
GWAS Traits (9)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
4
2
0
1.2
74.8
age at menarche
3
2
2
2.4
68.2
hip circumference
1
1
1
53.7
high density lipoprotein cholesterol measurement
1
1
1
48.5
triglyceride measurement
2
1
2
44.2
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
0
1.2
74.8
age at menarche
2
2.4
68.2
hip circumference
1
53.7
high density lipoprotein cholesterol measurement
1
48.5
triglyceride measurement
2
44.2
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (10)
1 – 5 of 10
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
vestigial like family member 3
719328
Mouse
MGI:1920819
73569
Rat
RGD:1560030
498038
Dog
vestigial like family member 3
VGNC:48259
607015
Horse
vestigial like family member 3
VGNC:24902
100069930
Species
Name
OMA
EggNOG
Inparanoid
Macaque
vestigial like family member 3
Mouse
Rat
Dog
vestigial like family member 3
Horse
vestigial like family member 3
Publication Statistics
PubMed Score 31.88
PubMed score by year
PubTator Score 11.60
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title