Protein Summary
Plays a role in the dynamic structure of centrosome-associated contractile fibers via its interaction with CETN2.
- ENST00000400288
- ENSP00000383145
- ENSG00000198089
- ENST00000400289
- ENSP00000383146
- ENST00000432498
- ENSP00000402679
- ENST00000540643
- ENSP00000443025
- KIAA0542
- PISD
- hSfi1p
- PPP1R139
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
transcription factor binding site profile | 0.88 | ||
transcription factor perturbation | 0.74 | ||
interacting protein | 0.73 | ||
transcription factor | 0.69 | ||
PubMedID | 0.67 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 62.23 (req: < 5)
Gene RIFs: 3 (req: <= 3)
Antibodies: 42 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 62.23 (req: >= 5)
Gene RIFs: 3 (req: > 3)
Antibodies: 42 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 5
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Expression Data (0 Tissues)
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
Active Ligands (0)
Protein-Protein Interactions (153)
CETN1
Novelty: 0.01208917
p_int: 0.999999994
p_wrong: 6e-9
Score: 0.925
Data Source: BioPlex,STRINGDB
Nearest Tclin Targets
Pathways (17)
Reactome (16)
PathwayCommons (1)
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
|---|---|---|---|---|---|
Reactome | AURKA Activation by TPX2 | ||||
Reactome | Anchoring of the basal body to the plasma membrane | ||||
Reactome | Cell Cycle | ||||
Reactome | Cell Cycle, Mitotic | ||||
Reactome | Centrosome maturation | ||||
Name | Explore in Pharos | Explore in Source | ||
|---|---|---|---|---|
AURKA Activation by TPX2 | ||||
Anchoring of the basal body to the plasma membrane | ||||
Cell Cycle | ||||
Cell Cycle, Mitotic | ||||
Centrosome maturation | ||||
Viral Interactions (0)
Gene Ontology Terms (8)
Functions (1)
Components (3)
Processes (4)
GO Term | Evidence | Assigned by | ||
|---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Disease Associations (null)
GWAS Traits (11)
Items per page:
1 – 5 of 11
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
|---|---|---|---|---|---|---|---|---|---|
neutrophil count | 4 | 1 | 4 | 64.5 | |||||
myeloid white cell count | 1 | 1 | 1 | 60.5 | |||||
type 2 diabetes mellitus | 1 | 1 | 0 | 1.1 | 54.8 | ||||
1 | 1 | 0 | 1.2 | 41.8 | |||||
Cleft palate | 1 | 1 | 0 | 1.2 | 41.8 | ||||
Items per page:
1 – 5 of 11
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
|---|---|---|---|---|---|---|---|
neutrophil count | 4 | 64.5 | |||||
myeloid white cell count | 1 | 60.5 | |||||
type 2 diabetes mellitus | 0 | 1.1 | 54.8 | ||||
0 | 1.2 | 41.8 | |||||
Cleft palate | 0 | 1.2 | 41.8 | ||||
Find similar targets by:
IDG Resources
Orthologs (11)
1 – 5 of 11
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|---|---|
Chimp | SFI1 centrin binding protein | VGNC:6012 | 458771 | |||||
Macaque | SFI1 centrin binding protein | 716833 | ||||||
Mouse | MGI:1926137 | 78887 | ||||||
Rat | RGD:1560636 | 305467 | ||||||
Dog | SFI1 centrin binding protein | VGNC:46075 | 486367 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|
Chimp | SFI1 centrin binding protein | |||||
Macaque | SFI1 centrin binding protein | |||||
Mouse | ||||||
Rat | ||||||
Dog | SFI1 centrin binding protein | |||||
Publication Statistics
PubMed Score 62.23
PubMed score by year
PubTator Score 9.36
PubTator score by year
Related Publications
Text Mined References (17)
GeneRif Annotations (3)
Items per page:
0 of 0
PMID | Year | Title |
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