Tbio DISP2 Protein dispatched homolog 2

Protein Summary

Description

This gene is one of two human homologs of a segment-polarity gene known as dispatched identified in Drosophila. The product of this gene may be required for normal Hedgehog (Hh) signaling during embryonic pattern formation. [provided by RefSeq, Jan 2017]

Uniprot Accession IDs

• A7MBM2
• Q6AHW3
• Q9C0C1

Gene Name

• DISP2

Ensembl ID

• ENST00000267889
• ENSP00000267889
• ENSG00000140323

Symbol

• C15orf36
• DISPB
• KIAA1742
• LINC00594
• DISPB
• C15orf36
• HsT16908
• LINC00594

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
transcription factor perturbation	0.8
histone modification site profile	0.71
tissue sample	0.67
cell type or tissue	0.63
PubMedID	0.51

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 12.96   (req: < 5)

Gene RIFs: 0   (req: <= 3)

Antibodies: 83   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 12.96   (req: >= 5)

Gene RIFs: 0   (req: > 3)

Antibodies: 83   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0