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Tdark
SIGLEC16
Sialic acid-binding Ig-like lectin 16

Protein Classes
Protein Summary
Description
Putative adhesion molecule that mediates sialic-acid dependent binding to cells.
Uniprot Accession IDs
Gene Name
Symbol
  • SIGLECP16
  • SIGLECP16
  • Siglec-P16
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
tissue sample
0.57
cell line
0.48
tissue
0.38
biological term
0.33
cell type or tissue
0.31


Related Tools
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 0   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 0   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-A6NMB1-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Pathways (3)
DAP12 interactions (R-HSA-2172127)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
DAP12 interactions
Reactome
Immune System
Reactome
Innate Immune System
Name
Explore in Pharos
Explore in Source
DAP12 interactions
Immune System
Innate Immune System
Gene Ontology Terms (7)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Protein-Protein Interactions (2)
1 – 2 of 2
SIGLEC10
Tbio
Novelty:  0.02858542
p_int:  1
Data Source:  BioPlex
TYROBP
Tbio
Family:  Enzyme
Novelty:  0.00410031
Data Source:  Reactome
Publication Statistics
PubTator Score  2.18

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer