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Tdark
RFPL4A
Ret finger protein-like 4A

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000434937
  • ENSP00000392936
  • ENSG00000223638

Symbol
  • RFPL4
  • RNF210
  • RFPL4
  • RNF210
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein domain
0.97
cellular component
0.64
cell line
0.61
tissue
0.59
protein complex
0.4


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.42   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 75   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.42   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 75   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Protein-Protein Interactions (11)
1 – 10 of 11
RFPL4B
Tdark
Novelty:  2.42779597
p_int:  0.999991493
p_ni:  1.54e-7
p_wrong:  0.000008354
Score:  0.717
Data Source:  BioPlex,STRINGDB
FAM90A1
Tdark
Novelty:  0.95155075
p_int:  0.999990875
p_ni:  1.85e-7
p_wrong:  0.00000894
Score:  0.862
Data Source:  BioPlex,STRINGDB
GDF9
Tbio
Novelty:  0.00258351
Score:  0.804
Data Source:  STRINGDB
TRIM61
Tdark
Novelty:  0.46482206
Score:  0.541
Data Source:  STRINGDB
NOBOX
Tbio
Family:  TF
Novelty:  0.01217542
Score:  0.516
Data Source:  STRINGDB
UBE2S
Tbio
Novelty:  0.00363304
Score:  0.492
Data Source:  STRINGDB
ZNF444
Tdark
Family:  TF
Novelty:  0.21564163
Score:  0.461
Data Source:  STRINGDB
H1FOO
Tbio
Novelty:  0.02189067
Score:  0.45
Data Source:  STRINGDB
PSMB1
Tclin
Family:  Enzyme
Novelty:  0.0255917
Score:  0.448
Data Source:  STRINGDB
UBE2A
Tbio
Novelty:  0.01670792
Score:  0.425
Data Source:  STRINGDB
Gene Ontology Terms (3)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
GWAS Traits (4)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
age at menopause
2
2
3
77.1
parental genotype effect measurement
1
1
1
46.9
birth weight
1
1
1
46.9
high density lipoprotein cholesterol measurement
1
1
1
21.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
age at menopause
3
77.1
parental genotype effect measurement
1
46.9
birth weight
1
46.9
high density lipoprotein cholesterol measurement
1
21.5
Publication Statistics
PubMed Score 3.42
PubMed score by year
PubTator Score 1.14
PubTator score by year