You are using an outdated browser. Please upgrade your browser to improve your experience.

Tdark
ELOA3D
Elongin-A3 member D

Protein Summary
Description
SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A is transcriptionally active and its transcription activity is strongly enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000620881
  • ENSP00000483981
  • ENSG00000274744

Symbol
  • TCEB3CL2
  • ELOA3L2
  • TCEB3CL2
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological process
0
biological term
0
cell line
0
cell type or tissue
0
cellular component
0


Related Tools
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 0   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 0   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-A6NLF2-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Pathways (22)
Disease (R-HSA-1643685)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 5 of 22
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Disease
Reactome
Formation of HIV elongation complex in the absence of HIV Tat
Reactome
Formation of HIV-1 elongation complex containing HIV-1 Tat
Reactome
Formation of RNA Pol II elongation complex
Reactome
Gene expression (Transcription)
Name
Explore in Pharos
Explore in Source
Disease
Formation of HIV elongation complex in the absence of HIV Tat
Formation of HIV-1 elongation complex containing HIV-1 Tat
Formation of RNA Pol II elongation complex
Gene expression (Transcription)
Gene Ontology Terms (2)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
InterPro
Protein-Protein Interactions (69)
1 – 10 of 69
ELOC
Tbio
Novelty: 0.00964847
Score: 0.969
Data Source: STRINGDB
ELOB
Tbio
Novelty: 0.01315739
Score: 0.939
Data Source: STRINGDB
POLR2A
Tbio
Family: Enzyme
Novelty: 0.00188323
Score: 0.924
Data Source: STRINGDB
POLR2B
Tbio
Family: Enzyme
Novelty: 0.0012624
Score: 0.92
Data Source: STRINGDB
TCEA1
Tbio
Novelty: 0.00547888
Score: 0.909
Data Source: STRINGDB
EAF1
Tbio
Novelty: 0.81120425
Score: 0.909
Data Source: STRINGDB
LEO1
Tbio
Family: Enzyme
Novelty: 0.00851903
Score: 0.908
Data Source: STRINGDB
IWS1
Tbio
Novelty: 0.08732963
Score: 0.908
Data Source: STRINGDB
EAF2
Tbio
Family: TF
Novelty: 0.08392419
Score: 0.907
Data Source: STRINGDB
NELFE
Tbio
Novelty: 0.02136256
Score: 0.906
Data Source: STRINGDB
Publication Statistics
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer