You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
RTL1
Retrotransposon-like protein 1

Protein Summary
Description
Plays an essential role in capillaries endothelial cells for the maintenance of feto-maternal interface and for development of the placenta. This gene is a retrotransposon-derived, paternally expressed imprinted gene that is highly expressed at the late fetal stage in both the fetus and placenta. It has an overlapping maternally expressed antisense transcript, which contains several microRNAs targeting the transcripts of this gene through an RNA interference (RNAi) mechanism. This gene is essential for maintenance of the fetal capillaries. [provided by RefSeq, Jul 2009]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000534062
  • ENSP00000435342
  • ENSG00000254656
  • ENST00000649591
  • ENSP00000497482

Symbol
  • MAR1
  • MART1
  • PEG11
  • HUR1
  • Mar1
  • MART1
  • PEG11
  • SIRH2
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.59
cell line
0.58
PubMedID
0.51
tissue
0.48
protein complex
0.4


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 119.5   (req: < 5)
Gene RIFs: 7   (req: <= 3)
Antibodies: 63   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 119.5   (req: >= 5)
Gene RIFs: 7   (req: > 3)
Antibodies: 63   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0