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Tdark
PRR19
Proline-rich protein 19

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000341747
  • ENSP00000342709
  • ENSG00000188368
  • ENST00000499536
  • ENSP00000445247
  • ENST00000598490
  • ENSP00000472962
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.7
cell line
0.61
transcription factor
0.57
cellular component
0.52
tissue
0.48


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.59   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 97   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.59   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 97   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (10)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
monocyte count
2
1
2
78.4
testosterone measurement
2
1
2
68.6
1
1
1
53.7
balding measurement
1
1
1
45.7
mean corpuscular hemoglobin concentration
1
1
1
39.6
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
monocyte count
2
78.4
testosterone measurement
2
68.6
1
53.7
balding measurement
1
45.7
mean corpuscular hemoglobin concentration
1
39.6
Orthologs (7)
1 – 5 of 7
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
proline rich 19
VGNC:2278
456075
Mouse
MGI:3648539
623131
Rat
RGD:1595416
681408
Dog
proline rich 19
VGNC:45042
612449
Horse
proline rich 19
VGNC:21901
100065213
Species
Name
OMA
EggNOG
Inparanoid
Chimp
proline rich 19
Mouse
Rat
Dog
proline rich 19
Horse
proline rich 19
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-A6NJB7-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Protein-Protein Interactions (18)
1 – 10 of 18
ANKRA2
Tbio
Novelty:  0.19358401
Score:  0.908
Data Source:  STRINGDB
RFXANK
Tbio
Novelty:  0.00355465
Score:  0.718
Data Source:  STRINGDB
LRP2
Tbio
Novelty:  0.00143258
Score:  0.713
Data Source:  STRINGDB
TMEM145
Tdark
Novelty:  2.30428448
Score:  0.709
Data Source:  STRINGDB
PAFAH1B3
Tbio
Family:  Enzyme
Novelty:  0.10517347
Score:  0.675
Data Source:  STRINGDB
ZNF607
Tdark
Family:  TF
Novelty:  3.26259479
Score:  0.649
Data Source:  STRINGDB
ZSCAN22
Tdark
Family:  TF
Novelty:  0.79698385
Score:  0.588
Data Source:  STRINGDB
ZNF480
Tdark
Family:  TF
Novelty:  0.46269256
Score:  0.571
Data Source:  STRINGDB
ALDH16A1
Tdark
Family:  Enzyme
Novelty:  0.21880567
Score:  0.512
Data Source:  STRINGDB
MEGF8
Tbio
Novelty:  0.24616449
Score:  0.497
Data Source:  STRINGDB
Publication Statistics
PubMed Score  1.59

PubMed score by year
PubTator Score  1

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer