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Tdark
METTL15
Probable methyltransferase-like protein 15

Protein Summary
Description
Probable S-adenosyl-L-methionine-dependent methyltransferase.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000303459
  • ENSP00000307251
  • ENSG00000169519
  • ENST00000406787
  • ENSP00000385507
  • ENST00000407364
  • ENSP00000384369
  • ENST00000437814
  • ENSP00000392806

Symbol
  • METT5D1
  • METT5D1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor binding site profile
0.81
cellular component
0.75
transcription factor
0.66
cell type or tissue
0.65
tissue sample
0.65


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 43   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 43   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein-Protein Interactions (59)
1 – 10 of 59
KLHL22
Tbio
Novelty: 0.50704225
p_int: 0.999997517
p_ni: 0.000002483
Data Source: BioPlex
RBFA
Tbio
Novelty: 0.12145749
p_int: 0.999996433
p_ni: 0.000003566
Score: 0.554
Data Source: BioPlex,STRINGDB
EMILIN1
Tbio
Novelty: 0.0305471
p_int: 0.999821434
p_ni: 0.000178564
p_wrong: 2e-9
Data Source: BioPlex
CD70
Tbio
Novelty: 0.00552433
p_int: 0.998504985
p_ni: 0.001490178
p_wrong: 0.000004838
Data Source: BioPlex
LIPT1
Tdark
Family: Enzyme
Novelty: 0.0746733
p_int: 0.995453435
p_ni: 0.004546557
p_wrong: 8e-9
Score: 0.373
Data Source: BioPlex,STRINGDB
IL13RA2
Tbio
Novelty: 0.04900852
p_int: 0.995124628
p_ni: 0.004875013
p_wrong: 3.59e-7
Data Source: BioPlex
LAMP3
Tbio
Novelty: 0.02024311
p_int: 0.99367359
p_ni: 0.006326407
p_wrong: 3e-9
Data Source: BioPlex
KBTBD7
Tdark
Novelty: 1.01449275
p_int: 0.992064045
p_ni: 0.007635054
p_wrong: 0.0003009
Data Source: BioPlex
GYPB
Tbio
Novelty: 0.00257625
p_int: 0.990072829
p_ni: 0.009926862
p_wrong: 3.08e-7
Data Source: BioPlex
CD79A
Tbio
Novelty: 0.00192293
p_int: 0.976894143
p_ni: 0.023105816
p_wrong: 4.1e-8
Data Source: BioPlex
Publication Statistics
Amino Acid Sequence
Residue Counts
Sequence
MLRYPYFCRMYKECLSCWLESGIPNLGVWPNRIHTTAEKYREYEAREQTDQTQAQELHRSQDRDFETMAK
1-70
LHIPVMVDEVVHCLSPQKGQIFLDMTFGSGGHTKAILQKESDIVLYALDRDPTAYALAEHLSELYPKQIR
70-140
AMLGQFSQAEALLMKAGVQPGTFDGVLMDLGCSSMQLDTPERGFSLRKDGPLDMRMDGGRYPDMPTAADV
140-210
VNALDQQALASILRTYGEEKHAKKIASAIVQARSIYPITRTQQLASIVAGAFPPSAIYTRKDLLQRSTHI
210-280
ATKTFQALRIFVNNELNELYTGLKTAQKFLRPGGRLVALSFHSLEDRIVKRFLLGISMTERFNLSVRQQV
280-350
MKTSQLGSDHENTEEVSMRRAPLMWELIHKKVLSPQDQDVQDNPRGRSAKLRAAIKL
350-407
MLRYPYFCRMYKECLSCWLESGIPNLGVWPNRIHTTAEKYREYEAREQTDQTQAQELHRSQDRDFETMAKLHIPVMVDEVVHCLSPQKGQIFLDMTFGSGGHTKAILQKESDIVLYALDRDPTAYALAEHLSELYPKQIRAMLGQFSQAEALLMKAGVQPGTFDGVLMDLGCSSMQLDTPERGFSLRKDGPLDMRMDGGRYPDMPTAADVVNALDQQALASILRTYGEEKHAKKIASAIVQARSIYPITRTQQLASIVAGAFPPSAIYTRKDLLQRSTHIATKTFQALRIFVNNELNELYTGLKTAQKFLRPGGRLVALSFHSLEDRIVKRFLLGISMTERFNLSVRQQVMKTSQLGSDHENTEEVSMRRAPLMWELIHKKVLSPQDQDVQDNPRGRSAKLRAAIKL