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Tbio
MSGN1
Mesogenin-1

Protein Summary
Description
Involved in specifying the paraxial, but not dorsal, mesoderm. May regulate the expression of T-box transcription factors required for mesoderm formation and differentiation (By similarity).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000281047
  • ENSP00000281047
  • ENSG00000151379

Symbol
  • MSOG
  • pMsgn1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
tissue
0.73
biological process
0.6
molecular function
0.49
phenotype
0.45
cell line
0.42


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 13.05   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 70   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 13.05   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 70   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 8
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (25)
TBX6
Tbio
Family:  TF
Novelty:  0.01060902
Score:  0.827
Data Source:  STRINGDB
ID1
Tbio
Family:  TF
Novelty:  0.00151069
Score:  0.755
Data Source:  STRINGDB
SMC6
Tbio
Novelty:  0.02450073
Score:  0.738
Data Source:  STRINGDB
ATP11B
Tbio
Family:  Transporter
Novelty:  0.08604515
Score:  0.691
Data Source:  STRINGDB
CCDC14
Tdark
Novelty:  0.62617082
Score:  0.684
Data Source:  STRINGDB
SPOCK3
Tbio
Novelty:  0.11871451
Score:  0.633
Data Source:  STRINGDB
UNCX
Tbio
Family:  TF
Novelty:  0.05605716
Score:  0.627
Data Source:  STRINGDB
HES7
Tbio
Family:  TF
Novelty:  0.02014919
Score:  0.624
Data Source:  STRINGDB
ANXA10
Tbio
Novelty:  0.01232803
Score:  0.623
Data Source:  STRINGDB
VSNL1
Tbio
Novelty:  0.01221371
Score:  0.592
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (22)
Find Similar Targets
Items per page:
1 – 5 of 22
Data Source
Name
Explore in Pharos
Explore in Source
WikiPathways
Mesodermal Commitment Pathway
WikiPathways
Mesodermal Commitment Pathway
WikiPathways
Mesodermal Commitment Pathway
WikiPathways
Mesodermal Commitment Pathway
WikiPathways
EDA Signalling in Hair Follicle Development
Name
Explore in Pharos
Explore in Source
Mesodermal Commitment Pathway
Mesodermal Commitment Pathway
Mesodermal Commitment Pathway
Mesodermal Commitment Pathway
EDA Signalling in Hair Follicle Development
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (9)
Find Similar Targets
Items per page:
10
1 – 5 of 5
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Sequence Alignment (ISA)
NTNU_SB
Inferred from Electronic Annotation (IEA)
Ensembl
Inferred from Electronic Annotation (IEA)
InterPro
Disease Associations ()
No disease associations found
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
total cholesterol measurement
1
1
1
24.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
total cholesterol measurement
1
24.5
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
mesogenin 1
VGNC:10723
470314
Macaque
mesogenin 1
715386
Mouse
MGI:1860483
56184
Rat
RGD:1587516
689864
Dog
mesogenin 1
VGNC:43437
482981
Species
Name
OMA
EggNOG
Inparanoid
Chimp
mesogenin 1
Macaque
mesogenin 1
Mouse
Rat
Dog
mesogenin 1
Publication Statistics
PubMed Score 13.05
PubMed score by year
PubTator Score 1.83
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title