Tdark TUBAL3 Tubulin alpha chain-like 3

Protein Summary

Description

Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (By similarity).

Uniprot Accession IDs

• A6NHL2
• B4DKL2
• Q4QQJ5
• Q9H6Z0

Gene Name

• TUBAL3

Ensembl ID

• ENST00000380419
• ENSP00000369784
• ENSG00000178462
• ENST00000479328
• ENSP00000418799

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
molecular function	0.93
protein domain	0.92
protein complex	0.75
cell type or tissue	0.67
interacting protein	0.64

Protein Classes

PANTHER Classes

Protein / Cytoskeletal Protein / Microtubule Family Cytoskeletal Protein / Tubulin / Tubulin Alpha Chain-like 3

DTO Classes

Protein / Cellular Structure / Microtubule Family Cytoskeletal Protein / Tubulin / Tubulin Alpha Chain-like 3

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.84   (req: < 5)

Gene RIFs: 2   (req: <= 3)

Antibodies: 169   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.84   (req: >= 5)

Gene RIFs: 2   (req: > 3)

Antibodies: 169   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0