You are using an outdated browser. Please upgrade your browser to improve your experience.

Tdark
TMEM191C
Transmembrane protein 191C

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000621561
  • ENSP00000489706
  • ENSG00000206140
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cellular component
0.84
cell line
0.71
tissue
0.71
tissue sample
0.62
histone modification site profile
0.56


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.03   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 0   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.03   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 0   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (19)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
lymphocyte count
2
2
2
93.7
red blood cell distribution width
3
2
3
91.6
neutrophil percentage of leukocytes
2
2
2
85.2
high density lipoprotein cholesterol measurement
1
1
1
82.7
apolipoprotein A 1 measurement
1
1
1
81.9
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
lymphocyte count
2
93.7
red blood cell distribution width
3
91.6
neutrophil percentage of leukocytes
2
85.2
high density lipoprotein cholesterol measurement
1
82.7
apolipoprotein A 1 measurement
1
81.9
Orthologs (1)
1 – 1 of 1
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
transmembrane protein 191C
697070
Species
Name
OMA
EggNOG
Inparanoid
Macaque
transmembrane protein 191C
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-A6NGB0-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (1)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Protein-Protein Interactions (25)
1 – 10 of 25
TMEM236
Tdark
Novelty:  2.30662044
Score:  0.731
Data Source:  STRINGDB
OR13C8
Tdark
Family:  oGPCR
Novelty:  1.99882539
Score:  0.727
Data Source:  STRINGDB
LRRC14B
Tdark
Novelty:  7.10619267
Score:  0.671
Data Source:  STRINGDB
TTC9
Tdark
Novelty:  0.1679064
Score:  0.648
Data Source:  STRINGDB
OTOGL
Tbio
Novelty:  0.11538923
Score:  0.609
Data Source:  STRINGDB
FAM47B
Tdark
Novelty:  5.65542292
Score:  0.588
Data Source:  STRINGDB
DNAH2
Tbio
Novelty:  0.12847351
Score:  0.544
Data Source:  STRINGDB
SLC10A7
Tbio
Family:  Transporter
Novelty:  0.15556211
Score:  0.544
Data Source:  STRINGDB
SH3BP1
Tbio
Novelty:  8.50014339
Score:  0.526
Data Source:  STRINGDB
ADGRF5
Tbio
Family:  GPCR
Novelty:  0.08145242
Score:  0.517
Data Source:  STRINGDB
Publication Statistics
PubMed Score  0.03

PubMed score by year
PubTator Score  0.25

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
Find similar targets by: