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Tdark
FAM24A
Protein FAM24A

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000368894
  • ENSP00000357889
  • ENSG00000203795
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
tissue
0.61
cell line
0.37
transcription factor
0.3
cell type or tissue
0.25
disease
0.25


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.05   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 0   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.05   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 0   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (8)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
red blood cell distribution width
4
4
4
96.5
low density lipoprotein cholesterol measurement
7
5
7
94.7
apolipoprotein B measurement
1
1
1
56.8
mean reticulocyte volume
1
1
1
56
reticulocyte measurement
1
1
1
48.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
red blood cell distribution width
4
96.5
low density lipoprotein cholesterol measurement
7
94.7
apolipoprotein B measurement
1
56.8
mean reticulocyte volume
1
56
reticulocyte measurement
1
48.5
Orthologs (4)
1 – 4 of 4
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
family with sequence similarity 24 member A
VGNC:12326
450796
Mouse
MGI:1915473
68223
Rat
RGD:1560958
499277
Dog
family with sequence similarity 24 member B
100683500
Species
Name
OMA
EggNOG
Inparanoid
Chimp
family with sequence similarity 24 member A
Mouse
Rat
Dog
family with sequence similarity 24 member B
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-A6NFZ4-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (1)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Protein-Protein Interactions (9)
1 – 9 of 9
IQCF6
Tdark
Novelty:  6.09485606
Score:  0.827
Data Source:  STRINGDB
CPXCR1
Tdark
Novelty:  0.44086412
Score:  0.697
Data Source:  STRINGDB
PRR30
Tdark
Novelty:  0.80276953
Score:  0.671
Data Source:  STRINGDB
GAREM2
Tdark
Novelty:  0.64211866
Score:  0.67
Data Source:  STRINGDB
RNF148
Tdark
Novelty:  0.38670797
Score:  0.667
Data Source:  STRINGDB
TTC9B
Tdark
Novelty:  0.25942345
Score:  0.447
Data Source:  STRINGDB
SLC25A47
Tbio
Family:  Transporter
Novelty:  0.57588107
Score:  0.424
Data Source:  STRINGDB
PCDHGC5
Tdark
Novelty:  0.39651826
Score:  0.42
Data Source:  STRINGDB
TSSK3
Tchem
Family:  Kinase
Novelty:  0.17000052
Score:  0.414
Data Source:  STRINGDB
Publication Statistics
PubMed Score  0.05

PubMed score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer