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Tdark
TMEM235
Transmembrane protein 235

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000374946
  • ENSP00000364084
  • ENSG00000204278
  • ENST00000421688
  • ENSP00000402790
  • ENST00000550981
  • ENSP00000447766
  • ENST00000551068
  • ENSP00000446514
  • ENST00000586400
  • ENSP00000466793

Symbol
  • ARGM1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cellular component
0.77
cell type or tissue
0.63
cell line
0.53
tissue
0.42
biological term
0.33


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.44   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 4   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.44   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 4   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (70)
OPALIN
Tdark
Novelty:  0.08221612
Score:  0.771
Data Source:  STRINGDB
MAG
Tchem
Novelty:  0.00085621
Score:  0.702
Data Source:  STRINGDB
HAPLN2
Tbio
Novelty:  0.13206172
Score:  0.608
Data Source:  STRINGDB
CLDND1
Tbio
Novelty:  0.06681793
Score:  0.603
Data Source:  STRINGDB
KCNJ9
Tbio
Family:  IC
Novelty:  0.02279401
Score:  0.578
Data Source:  STRINGDB
NTSR2
Tchem
Family:  GPCR
Novelty:  0.00699381
Score:  0.561
Data Source:  STRINGDB
HTR5A
Tchem
Family:  GPCR
Novelty:  0.0160551
Score:  0.537
Data Source:  STRINGDB
CA10
Tbio
Family:  Enzyme
Novelty:  0.01053152
Score:  0.531
Data Source:  STRINGDB
TCEAL6
Tdark
Novelty:  0.88185411
Score:  0.528
Data Source:  STRINGDB
MT3
Tbio
Novelty:  0.00321947
Score:  0.526
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (16)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
HbA1c measurement
2
7
8
98.4
red blood cell distribution width
3
4
6
97.2
reticulocyte count
7
5
12
94.2
mean corpuscular volume
1
2
2
93.3
reticulocyte measurement
3
3
5
91.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
HbA1c measurement
8
98.4
red blood cell distribution width
6
97.2
reticulocyte count
12
94.2
mean corpuscular volume
2
93.3
reticulocyte measurement
5
91.5
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (6)
1 – 5 of 6
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Mouse
MGI:3651706
546519
Rat
RGD:1591141
688285
Dog
transmembrane protein 235
VGNC:47545
491549
Horse
transmembrane protein 235 [Source:HGNC Symbol;Acc:HGNC:27563]
Cow
transmembrane protein 235
VGNC:36048
536606
Species
Name
OMA
EggNOG
Inparanoid
Mouse
Rat
Dog
transmembrane protein 235
Horse
transmembrane protein 235 [Source:HGNC Symbol;Acc:HGNC:27563]
Cow
transmembrane protein 235
Publication Statistics
PubMed Score 0.44
PubMed score by year
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Related Publications
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0 of 0
PMID
Year
Title