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Tdark
TBC1D3F
TBC1 domain family member 3F

Protein Summary
Description
Acts as a GTPase activating protein for RAB5. Does not act on RAB4 or RAB11 (By similarity).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000614193
  • ENSP00000477822
  • ENSG00000282087
  • ENST00000621026
  • ENSP00000482590
  • ENSG00000275954

Symbol
  • TBC1D3E
  • TBC1D3
  • TBC1D3G
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
0.85
tissue sample
0.65
cell type or tissue
0.61
cell line
0.54
tissue
0.42


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 0   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 0   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Gene Ontology Terms (5)
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Protein-Protein Interactions (8)
1 – 8 of 8
TBC1D3
Tdark
Novelty: 0.33337743
p_int: 0.999999992
p_wrong: 8e-9
Score: 0.695
Data Source: BioPlex,STRINGDB
C10orf113
Tdark
Score: 0.642
Data Source: STRINGDB
C17orf78
Tdark
Score: 0.56
Data Source: STRINGDB
RAB5A
Tbio
Family: Enzyme
Novelty: 0.00149542
Score: 0.442
Data Source: STRINGDB
ARHGAP23
Tdark
Family: Enzyme
Novelty: 3.75116681
Score: 0.44
Data Source: STRINGDB
TADA2A
Tbio
Family: TF
Novelty: 0.11952758
Score: 0.43
Data Source: STRINGDB
SYNRG
Tdark
Novelty: 0.01949589
Score: 0.422
Data Source: STRINGDB
TBC1D5
Tbio
Novelty: 0.23954373
Score: 0.407
Data Source: STRINGDB
Publication Statistics
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer