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Tdark
TRAPPC13
Trafficking protein particle complex subunit 13

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000231526
  • ENSP00000231526
  • ENSG00000113597
  • ENST00000399438
  • ENSP00000382367
  • ENST00000438419
  • ENSP00000409231
  • ENST00000505553
  • ENSP00000423405

Symbol
  • C5orf44
  • SHLD3
  • C5orf44
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.92
transcription factor perturbation
0.74
kinase perturbation
0.71
transcription factor binding site profile
0.71
cellular component
0.63


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.3   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 44   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.3   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 44   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
brain stem volume measurement
1
1
0
8.2
66.8
feeling tense measurement
1
1
0
6
31.4
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
brain stem volume measurement
0
8.2
66.8
feeling tense measurement
0
6
31.4
Orthologs (15)
1 – 5 of 15
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
trafficking protein particle complex 13
VGNC:13610
461842
Macaque
trafficking protein particle complex 13
696521
Mouse
MGI:1914225
66975
Rat
RGD:1306583
294709
Dog
trafficking protein particle complex 13
VGNC:53302
478079
Species
Name
OMA
EggNOG
Inparanoid
Chimp
trafficking protein particle complex 13
Macaque
trafficking protein particle complex 13
Mouse
Rat
Dog
trafficking protein particle complex 13
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-A5PLN9-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Pathways (4)
Membrane Trafficking (R-HSA-199991)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 4 of 4
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Membrane Trafficking
Reactome
RAB GEFs exchange GTP for GDP on RABs
Reactome
Rab regulation of trafficking
Reactome
Vesicle-mediated transport
Name
Explore in Pharos
Explore in Source
Membrane Trafficking
RAB GEFs exchange GTP for GDP on RABs
Rab regulation of trafficking
Vesicle-mediated transport
Gene Ontology Terms (2)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Traceable Author Statement (TAS)
Reactome
Protein-Protein Interactions (35)
1 – 10 of 35
TRAPPC12
Tbio
Novelty:  0.09847363
p_int:  1
Score:  0.993
Data Source:  BioPlex,STRINGDB
TRAPPC5
Tdark
Novelty:  0.22558077
p_int:  0.999999921
p_ni:  7e-8
p_wrong:  9e-9
Score:  0.993
Data Source:  BioPlex,STRINGDB
TRAPPC1
Tbio
Novelty:  0.09781468
p_int:  0.999999714
p_ni:  2.84e-7
p_wrong:  2e-9
Score:  0.994
Data Source:  BioPlex,STRINGDB
TRAPPC2
Tbio
Novelty:  0.02016231
p_int:  0.999999683
p_ni:  3.17e-7
Score:  0.988
Data Source:  BioPlex,STRINGDB
TBC1D14
Tbio
Novelty:  0.25089884
p_int:  0.999830797
p_ni:  0.000167693
p_wrong:  0.00000151
Score:  0.891
Data Source:  BioPlex,STRINGDB
DNAJC10
Tbio
Novelty:  0.02258366
p_int:  0.999269978
p_ni:  0.000730022
Score:  0.187
Data Source:  BioPlex,STRINGDB
COG6
Tbio
Novelty:  0.02874093
p_int:  0.983365186
p_ni:  0.016634814
Score:  0.219
Data Source:  BioPlex,STRINGDB
RAB43
Tbio
Family:  Enzyme
Novelty:  0.07527576
p_int:  0.982018118
p_ni:  0.001442292
p_wrong:  0.01653959
Data Source:  BioPlex
UBB
Tbio
Novelty:  0.00661254
p_int:  0.968160833
p_ni:  0.031839167
Score:  0.156
Data Source:  BioPlex,STRINGDB
TRAPPC8
Tdark
Novelty:  0.07711264
Score:  0.984
Data Source:  STRINGDB
Publication Statistics
PubMed Score  2.30

PubMed score by year
PubTator Score  0.34

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer