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Tdark
RGSL1
Regulator of G-protein signaling protein-like

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000294854
  • ENSP00000457748
  • ENSG00000121446

Symbol
  • RGSL
  • RGSL2
  • RGSL
  • RGSL2
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.88
tissue sample
0.54
tissue
0.46
chemical
0.41
protein complex
0.41


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.76   (req: < 5)
Gene RIFs: 4   (req: <= 3)
Antibodies: 5   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.76   (req: >= 5)
Gene RIFs: 4   (req: > 3)
Antibodies: 5   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
chronotype measurement
1
1
0
1.3
71.9
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
chronotype measurement
0
1.3
71.9
Pathways (6)
G alpha (i) signalling events (R-HSA-418594)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 5 of 6
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
G alpha (i) signalling events
Reactome
G alpha (q) signalling events
Reactome
G alpha (z) signalling events
Reactome
GPCR downstream signalling
Reactome
Signal Transduction
Name
Explore in Pharos
Explore in Source
G alpha (i) signalling events
G alpha (q) signalling events
G alpha (z) signalling events
GPCR downstream signalling
Signal Transduction
Gene Ontology Terms (1)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Protein-Protein Interactions (30)
1 – 10 of 30
TEX35
Tdark
Novelty: 0.5605055
Score: 0.91
Data Source: STRINGDB
RALGPS2
Tdark
Novelty: 0.32828463
Score: 0.908
Data Source: STRINGDB
GNAI3
Tbio
Novelty: 0.03484857
Score: 0.9
Data Source: STRINGDB
GNAT3
Tbio
Novelty: 0.00702357
Score: 0.9
Data Source: STRINGDB
GNA11
Tbio
Novelty: 0.00128664
Score: 0.9
Data Source: STRINGDB
GNA14
Tbio
Novelty: 0.0587776
Score: 0.9
Data Source: STRINGDB
GNA15
Tbio
Novelty: 0.00159196
Score: 0.9
Data Source: STRINGDB
GNAQ
Tbio
Novelty: 0.0008997
Score: 0.9
Data Source: STRINGDB
GNAZ
Tbio
Novelty: 0.02008523
Score: 0.9
Data Source: STRINGDB
GNAI1
Tbio
Novelty: 0.0488971
Score: 0.9
Data Source: STRINGDB
Publication Statistics
PubMed Score  3.76

PubMed score by year
PubTator Score  2.62

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer