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Tbio
XIRP2
Xin actin-binding repeat-containing protein 2

Protein Summary
Description
Protects actin filaments from depolymerization.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000409043
  • ENSP00000386454
  • ENSG00000163092
  • ENST00000409195
  • ENSP00000386840
  • ENST00000409273
  • ENSP00000387255
  • ENST00000409605
  • ENSP00000386981
  • ENST00000409728
  • ENSP00000386619
  • ENST00000628543
  • ENSP00000486198

Symbol
  • CMYA3
  • CMYA3
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
trait
0.61
cell type or tissue
0.6
cell line
0.59
tissue
0.56
phenotype
0.55


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 16.3   (req: < 5)
Gene RIFs: 6   (req: <= 3)
Antibodies: 43   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 16.3   (req: >= 5)
Gene RIFs: 6   (req: > 3)
Antibodies: 43   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
self reported educational attainment
1
1
1
52
1
1
0
1.3
31.9
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
self reported educational attainment
1
52
0
1.3
31.9
Protein Data Bank (1)
1 – 1 of 1
PDB Structure Id
Ligand
Method
Resolution (Å)
M.W. (kDa)
Pub Year
Title
PDB Structure Id
M.W.
Resolution
Pub Year
Gene Ontology Terms (8)
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Mutant Phenotype (IMP)
UniProtKB
Inferred from Electronic Annotation (IEA)
Ensembl
Protein-Protein Interactions (31)
1 – 10 of 31
ACTN2
Tbio
Novelty: 0.00615882
Score: 0.686
Data Source: STRINGDB
FLNC
Tbio
Novelty: 0.00463205
Score: 0.658
Data Source: STRINGDB
MEF2A
Tbio
Family: TF
Novelty: 0.00439393
Score: 0.641
Data Source: STRINGDB
NRAP
Tbio
Novelty: 0.15548332
Score: 0.628
Data Source: STRINGDB
NEBL
Tbio
Novelty: 0.02155964
Score: 0.581
Data Source: STRINGDB
FSCN2
Tbio
Novelty: 0.04059985
Score: 0.548
Data Source: STRINGDB
NEB
Tbio
Novelty: 0.00174728
Score: 0.539
Data Source: STRINGDB
CNBD1
Tdark
Novelty: 1.13449711
Score: 0.536
Data Source: STRINGDB
MYOT
Tbio
Novelty: 0.00888671
Score: 0.524
Data Source: STRINGDB
TTC29
Tdark
Novelty: 0.1887357
Score: 0.491
Data Source: STRINGDB
Publication Statistics
PubMed Score  16.30

PubMed score by year
PubTator Score  8.49

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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