Tbio XIRP2 Xin actin-binding repeat-containing protein 2

Protein Summary

Description

Protects actin filaments from depolymerization.

Uniprot Accession IDs

• A4UGR9
• A0PJ94
• B2BBS0
• B2BBS1
• B2BBS4
• B3KVH0
• J3KNB1
• Q53R52
• Q5MJ67
• Q702N7
• Q86T36
• Q86T38
• Q86T46
• Q86T51
• Q86T53
• Q86T55
• Q86T79
• Q86TB6
• Q8N1M9
• Q8N3R5
• Q8TBV6

Gene Name

• XIRP2

Ensembl ID

• ENST00000409043
• ENSP00000386454
• ENSG00000163092
• ENST00000409195
• ENSP00000386840
• ENST00000409273
• ENSP00000387255
• ENST00000409605
• ENSP00000386981
• ENST00000409728
• ENSP00000386619
• ENST00000628543
• ENSP00000486198

Symbol

• CMYA3
• CMYA3

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
trait	0.61
cell type or tissue	0.6
cell line	0.59
tissue	0.56
phenotype	0.55

Protein Classes

PANTHER Classes

Protein / Cytoskeletal Protein / Actin Family Cytoskeletal Protein / Xin Actin-binding Repeat-containing Protein 2

DTO Classes

Protein / Cellular Structure / Actin Family Cytoskeletal Protein / Xin Actin-binding Repeat-containing Protein 2

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 20   (req: < 5)

Gene RIFs: 7   (req: <= 3)

Antibodies: 43   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 20   (req: >= 5)

Gene RIFs: 7   (req: > 3)

Antibodies: 43   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0