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Tdark
EFCAB5
EF-hand calcium-binding domain-containing protein 5

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000394835
  • ENSP00000378312
  • ENSG00000176927
  • ENST00000440741
  • ENSP00000393095
  • ENST00000536908
  • ENSP00000440619
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.87
protein domain
0.73
cell line
0.64
tissue sample
0.64
tissue
0.57


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.41   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 34   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.41   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 34   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (17)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
leukocyte count
1
1
1
80.4
mean platelet volume
1
1
1
78
heel bone mineral density
1
1
1
77.9
myeloid white cell count
1
1
1
71.6
red blood cell distribution width
1
1
1
60.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
leukocyte count
1
80.4
mean platelet volume
1
78
heel bone mineral density
1
77.9
myeloid white cell count
1
71.6
red blood cell distribution width
1
60.5
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
EF-hand calcium binding domain 5
VGNC:9269
454552
Macaque
EF-hand calcium binding domain 5
717087
Mouse
MGI:2442440
319634
Dog
EF-hand calcium binding domain 5
VGNC:40216
480634
Horse
EF-hand calcium binding domain 5
VGNC:52378
100072197
Species
Name
OMA
EggNOG
Inparanoid
Chimp
EF-hand calcium binding domain 5
Macaque
EF-hand calcium binding domain 5
Mouse
Dog
EF-hand calcium binding domain 5
Horse
EF-hand calcium binding domain 5
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-A4FU69-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (1)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
InterPro
Protein-Protein Interactions (24)
1 – 10 of 24
NSRP1
Tbio
Novelty:  0.22397628
Score:  0.714
Data Source:  STRINGDB
KIAA2012
Tdark
Novelty:  21
Score:  0.629
Data Source:  STRINGDB
PRDM15
Tbio
Family:  TF; Epigenetic
Novelty:  0.17392284
Score:  0.581
Data Source:  STRINGDB
EXOC3L4
Tdark
Novelty:  0.65394237
Score:  0.548
Data Source:  STRINGDB
UNC45A
Tbio
Novelty:  0.07503761
Score:  0.536
Data Source:  STRINGDB
FAM186A
Tdark
Novelty:  2.29255942
Score:  0.536
Data Source:  STRINGDB
KIAA1614
Tdark
Novelty:  3.54151008
Score:  0.529
Data Source:  STRINGDB
TRIM59
Tbio
Novelty:  0.04240864
Score:  0.522
Data Source:  STRINGDB
C21orf58
Tdark
Novelty:  1.16236162
Score:  0.511
Data Source:  STRINGDB
KPNA4
Tbio
Novelty:  0.01326511
Score:  0.51
Data Source:  STRINGDB
Publication Statistics
PubMed Score  1.41

PubMed score by year
PubTator Score  1.54

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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