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Tdark
MBLAC1
Metallo-beta-lactamase domain-containing protein 1

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000398075
  • ENSP00000381150
  • ENSG00000214309
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.65
tissue sample
0.62
cellular component
0.52
transcription factor binding site profile
0.49
transcription factor
0.45


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.05   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 16   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.05   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 16   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (18)
H1FNT
Tdark
Novelty:  0.05593238
p_int:  0.996740942
p_ni:  0.000055553
p_wrong:  0.003203504
Score:  0.685
Data Source:  BioPlex,STRINGDB
CLP1
Tbio
Family:  Enzyme
Novelty:  0.04643806
p_int:  0.756159944
p_ni:  0.243840056
Score:  0.54
Data Source:  BioPlex,STRINGDB
MBLAC2
Tdark
Family:  Enzyme
Novelty:  0.47407992
Score:  0.67
Data Source:  STRINGDB
HAGHL
Tdark
Family:  Enzyme
Novelty:  0.43436043
Score:  0.653
Data Source:  STRINGDB
FHAD1
Tdark
Novelty:  0.55401917
Score:  0.567
Data Source:  STRINGDB
ELFN1
Tbio
Novelty:  0.13428675
Score:  0.557
Data Source:  STRINGDB
NEURL2
Tdark
Novelty:  0.29029379
Score:  0.551
Data Source:  STRINGDB
ZNF676
Tdark
Family:  TF
Novelty:  0.23073578
Score:  0.547
Data Source:  STRINGDB
LACTB2
Tbio
Family:  Enzyme
Novelty:  0.1868172
Score:  0.53
Data Source:  STRINGDB
SPRY3
Tbio
Novelty:  0.06114906
Score:  0.507
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (8)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
hematocrit
1
1
1
78.3
FEV/FEC ratio
1
1
1
62.5
body height
1
1
1
62.1
1
1
0
1.3
61
1
1
0
1.1
37.6
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
hematocrit
1
78.3
FEV/FEC ratio
1
62.5
body height
1
62.1
0
1.3
61
0
1.1
37.6
IDG Resources
No IDG generated resources found
Orthologs (8)
1 – 5 of 8
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
metallo-beta-lactamase domain containing 1
VGNC:4421
463590
Mouse
MGI:2679717
330216
Rat
RGD:1306932
304346
Horse
metallo-beta-lactamase domain containing 1
VGNC:20012
100068735
Cow
metallo-beta-lactamase domain containing 1
VGNC:31281
505636
Species
Name
OMA
EggNOG
Inparanoid
Chimp
metallo-beta-lactamase domain containing 1
Mouse
Rat
Horse
metallo-beta-lactamase domain containing 1
Cow
metallo-beta-lactamase domain containing 1
Publication Statistics
PubMed Score 3.05
PubMed score by year
PubTator Score 1.81
PubTator score by year
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Related Publications
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0 of 0
PMID
Year
Title