Tdark TMEM120B Transmembrane protein 120B

Protein Summary

Description

Necessary for efficient adipogenesis.

Uniprot Accession IDs

• A0PK00
• A0PK01
• B3KX33

Gene Name

• TMEM120B

Ensembl ID

• ENST00000342607
• ENSP00000345152
• ENSG00000188735
• ENST00000449592
• ENSP00000404991

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
histone modification site profile	0.89
transcription factor	0.73
transcription factor binding site profile	0.73
small molecule perturbation	0.7
tissue sample	0.63

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.79   (req: < 5)

Gene RIFs: 2   (req: <= 3)

Antibodies: 35   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.79   (req: >= 5)

Gene RIFs: 2   (req: > 3)

Antibodies: 35   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0