zolpidem
An imidazopyridine derivative and short-acting GABA-A receptor agonist that is used for the treatment of INSOMNIA.
Ligand Summary
Target Activities
Items per page:
10
1 – 6 of 6
GABRA1
Gamma-aminobutyric acid receptor subunit alpha-1
8 Activities
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1 – 8 of 8
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
EC50 | 6.7 | J. Med. Chem., (2002) 45:23:5043 | ||||
EC50 | 6.72 | J. Biol. Chem., (2007) 282:36:26316 | ||||
IC50 | 6.89 | Bioorg. Med. Chem. Lett., (1997) 7:17:2277 | ||||
Ki | 7.21 | J. Med. Chem., (2008) 51:22:7243 | ||||
IC50 | 7.85 | Bioorg. Med. Chem. Lett., (1997) 7:17:2277 | ||||
EC50 | 6.7033 | POSITIVE ALLOSTERIC MODULATOR | ||||
Ki | 7.5735 | POSITIVE ALLOSTERIC MODULATOR | ||||
Ki | 7.68 | ALLOSTERIC MODULATOR | ||||
GABRG2
Gamma-aminobutyric acid receptor subunit gamma-2
5 Activities
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1 – 5 of 5
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
EC50 | 6.7033 | POSITIVE ALLOSTERIC MODULATOR | ||||
Ki | 7.5735 | POSITIVE ALLOSTERIC MODULATOR | ||||
Ki | 6.8069 | POSITIVE ALLOSTERIC MODULATOR | ||||
Ki | 6.1643 | POSITIVE ALLOSTERIC MODULATOR | ||||
Ki | 6.4168 | POSITIVE ALLOSTERIC MODULATOR | ||||
GABRA2
Gamma-aminobutyric acid receptor subunit alpha-2
3 Activities
Items per page:
1 – 3 of 3
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
EC50 | 6.13 | J. Med. Chem., (2002) 45:23:5043 | ||||
Ki | 6.11999989 | |||||
Ki | 6.8069 | POSITIVE ALLOSTERIC MODULATOR | ||||
GABRA3
Gamma-aminobutyric acid receptor subunit alpha-3
3 Activities
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1 – 3 of 3
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Ki | 5.67000008 | |||||
Ki | 6.1643 | POSITIVE ALLOSTERIC MODULATOR | ||||
Ki | 6.4168 | POSITIVE ALLOSTERIC MODULATOR | ||||
GABRB3
Gamma-aminobutyric acid receptor subunit beta-3
3 Activities
Items per page:
1 – 3 of 3
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Ki | 7.5735 | POSITIVE ALLOSTERIC MODULATOR | ||||
Ki | 6.8069 | POSITIVE ALLOSTERIC MODULATOR | ||||
Ki | 6.4168 | POSITIVE ALLOSTERIC MODULATOR | ||||
GABRB2
Gamma-aminobutyric acid receptor subunit beta-2
2 Activities
Items per page:
1 – 2 of 2
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
EC50 | 6.7033 | POSITIVE ALLOSTERIC MODULATOR | ||||
Ki | 6.1643 | POSITIVE ALLOSTERIC MODULATOR | ||||