valproic acid
A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
Ligand Summary
Target Activities
HDAC1
Histone deacetylase 1
1 Activities
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IC50 | 3.4 | |||||
ALDH5A1
Succinate-semialdehyde dehydrogenase, mitochondrial
1 Activities
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INHIBITOR | ||||||