ubenimex
Ligand Summary
growth inhibitor; RN given refers to ((L-Leu)-(S-(R*,S*)))-isomer; structure
UNII: I0J33N5627
PubChem: 6992132
ChEMBL: CHEMBL29292
DrugCentral: 2787
LyCHI: PC6C6DX4QP1H
Target Activities
LTA4H
Leukotriene A-4 hydrolase
5 Activities
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1 – 5 of 5
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 6.58 | ACS Med Chem Lett, (2020) 11:6:1244 | ||||
IC50 | 6.52 | Bioorg Med Chem, (2016) 24:21:5243 | ||||
Ki | 6.5 | Bioorg Med Chem, (2016) 24:21:5243 | ||||
IC50 | 6.3 | Bioorg. Med. Chem., (2011) 19:4:1434 | ||||
IC50 | 6.3 | |||||
LAP3
Cytosol aminopeptidase
3 Activities
Items per page:
1 – 3 of 3
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Ki | 9.22 | J. Med. Chem., (2003) 46:13:2641 | ||||
Ki | 7.7 | J. Med. Chem., (1988) 31:11:2193 | ||||
Ki | 9.22 | |||||
ANPEP
Aminopeptidase N
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 6.1 | Eur J Med Chem, (2017) 139:None:325 | ||||