triamterene
A pteridinetriamine compound that inhibits SODIUM reabsorption through SODIUM CHANNELS in renal EPITHELIAL CELLS.
Ligand Summary
NCATS Inxight: Drugs: triamterene
ChEMBL: CHEMBL585
DrugCentral: 2728
LyCHI: HVBUKXJVYVL3
Target Activities
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SCNN1A
Amiloride-sensitive sodium channel subunit alpha
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 5.30000019 | BLOCKER | ||||
SCNN1B
Amiloride-sensitive sodium channel subunit beta
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 5.30000019 | BLOCKER | ||||
SCNN1G
Amiloride-sensitive sodium channel subunit gamma
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 5.30000019 | BLOCKER | ||||