You are using an outdated browser. Please upgrade your browser to improve your experience.

trametinib

Ligand Summary
Ligand Structure
Rendered image for the query structure
Description
a reversible inhibitor of mitogen-activated extracellular signal-regulated kinase 1 (MEK1) and MEK2 activation and of MEK1 and MEK2 kinase activity. MEK proteins are upstream regulators of the extracellular signal-related kinase (ERK) pathway, which promotes cellular proliferation
Synonyms & Links
Guide to Pharmacology: 6495
DrugCentral: 4802
LyCHI:  T5HZJQ4ZPZ9W


Target Activities