tirofiban
Ligand Summary
a reversible antagonist of fibrinogen binding to the GP IIb/IIIa receptor, the major platelet surface receptor involved in platelet aggregation, when administered intravenously inhibits ex vivo platelet aggregation in a dose- and concentration-dependent manner
UNII: GGX234SI5H
PubChem: 40466968
ChEMBL: CHEMBL916
DrugCentral: 2680
LyCHI: 9WTWYH1JU53L
Target Activities
ITGB3
Integrin beta-3
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
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IC50 | 7.96 | INHIBITOR | ||||
ITGA2B
Integrin alpha-IIb
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
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IC50 | 7.96 | INHIBITOR | ||||