tirabrutinib hydrochloride
Ligand Summary
Tirabrutinib is a potent and selective Bruton’s tyrosine kinase (BTK) inhibitor that irreversibly and covalently binds to BTK Cys-481 in B cells and inhibits aberrant B cell receptor signalling in B cell-related cancers and autoimmune diseases.
UNII: LXG44NDL2T
PubChem: 54755438
ChEMBL: CHEMBL4071161
DrugCentral: 5423
LyCHI: S9QKYJ1XVN7L
Target Activities
6 Activities
Items per page:
1 – 6 of 6
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Kd | ||||||
IC50 | ||||||
Kd | ||||||
IC50 | ||||||
IC50 | INHIBITOR | |||||
IC50 | INHIBITOR | |||||