tazemetostat
Ligand Summary
Tazemetostat is an inhibitor of the methyltransferase, EZH2, and some EZH2 gain-of-function mutations including Y646X and A687V. Tazemetostat also inhibited EZH1 with a half-maximal inhibitory concentration (IC50) of 392 nM, approximately 36 times higher than the IC50 for inhibition of EZH2
UNII: Q40W93WPE1
PubChem: 66558664
Guide to Pharmacology: 7011
ChEMBL: CHEMBL3414621
DrugCentral: 5380
LyCHI: ZKMT6LPDYPMY
Target Activities
28 Activities
Items per page:
1 – 10 of 28
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