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sulindac

Ligand Summary
Ligand Structure
Rendered image for the query structure
Description
A sulfinylindene derivative prodrug whose sulfinyl moiety is converted in vivo to an active NSAID analgesic. Specifically, the prodrug is converted by liver enzymes to a sulfide which is excreted in the bile and then reabsorbed from the intestine. This helps to maintain constant blood levels with reduced gastrointestinal side effects.
Synonyms & Links
Guide to Pharmacology: 5425
DrugCentral: 2534
LyCHI:  CLRLMAWF3NSM


Target Activities