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selumetinib

Ligand Summary
Ligand Structure
Rendered image for the query structure
Description
Selumetinib is an inhibitor of mitogen-activated protein kinase kinases 1 and 2 (MEK1/2). MEK1/2 proteins are upstream regulators of the extracellular signal-related kinase (ERK) pathway. Both MEK and ERK are critical components of the RAS-regulated RAF-MEK-ERK pathway, which is often activated in different types of cancers
Synonyms & Links
DrugCentral: 5388
LyCHI:  T5L9Y2W2CV11


Target Activities