rupatadine
Ligand Summary
Rupatadine is a second-generation antihistamine, long-acting histamine antagonist with selective peripheral H1-receptor and platelet activating factor (PAF) antagonistic activities. Some of the metabolites (desloratadine and its hydroxylated metabolites) retain an antihistaminic activity and may partially contribute to the overall efficacy of the drug, maintaining activity for up to 24 hours.
UNII: 2AE8M83G3E
PubChem: 133017
Guide to Pharmacology: 10103
ChEMBL: CHEMBL91397
DrugCentral: 2413
LyCHI: F9AYB5KBYU5V
Target Activities
5 Activities
Items per page:
1 – 5 of 5
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
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IC50 | ||||||
Ki | ||||||
IC50 | ||||||
Ki | ||||||
IC50 | ANTAGONIST | |||||