rufinamide
Ligand Summary
The precise mechanism(s) by which rufinamide exerts its antiepileptic effect is unknown. The results of in vitro studies suggest that the principal mechanism of action of rufinamide is modulation of the activity of sodium channels and, in particular, prolongation of the inactive state of the channel.
UNII: WFW942PR79
PubChem: 129228
ChEMBL: CHEMBL1201754
DrugCentral: 3534
LyCHI: 89D44GBLRPKK
Target Activities
11 Activities
Items per page:
1 – 10 of 11
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
---|---|---|---|---|---|---|
Ki | ||||||
BLOCKER | ||||||
BLOCKER | ||||||
BLOCKER | ||||||
BLOCKER | ||||||
BLOCKER | ||||||
BLOCKER | ||||||
BLOCKER | ||||||
BLOCKER | ||||||
BLOCKER | ||||||