ropivacaine
An anilide used as a long-acting local anesthetic. It has a differential blocking effect on sensory and motor neurons.
Ligand Summary
UNII: 7IO5LYA57N
PubChem: 175805
Guide to Pharmacology: 7602
ChEMBL: CHEMBL1077896
DrugCentral: 2403
LyCHI: D4LXA9D256G2
Target Activities
SCN5A
Sodium channel protein type 5 subunit alpha
3 Activities
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1 – 3 of 3
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 4.56 | |||||
IC50 | 3.49 | |||||
IC50 | 4.56 | BLOCKER | ||||
SCN1A
Sodium channel protein type 1 subunit alpha
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
BLOCKER | ||||||
SCN2A
Sodium channel protein type 2 subunit alpha
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
BLOCKER | ||||||
SCN3A
Sodium channel protein type 3 subunit alpha
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
BLOCKER | ||||||
SCN4A
Sodium channel protein type 4 subunit alpha
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
BLOCKER | ||||||
SCN8A
Sodium channel protein type 8 subunit alpha
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
BLOCKER | ||||||
SCN9A
Sodium channel protein type 9 subunit alpha
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
BLOCKER | ||||||
SCN10A
Sodium channel protein type 10 subunit alpha
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
BLOCKER | ||||||