Pharos : Ligand Details - romidepsin

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Ligand Summary

Ligand Structure

Rendered image for the query structure

Synonyms & Links

Name: Romidepsin

PubChem: 11947684

ChEMBL: CHEMBL3310505

LyCHI: TRWTPW951LKS

Target Activities

Explore Associated and Predicted Targets

HDAC1

Tclin

Histone deacetylase 1

4 Activities

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1 – 4 of 4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	8.8		J Med Chem, (2020) 63:1:23	31415174

IC50	8.62		MedChemComm, (2019) 10:4:538

IC50	7.44		Eur J Med Chem, (2019) 183:None:111691	31536895

IC50	7.44		Eur J Med Chem, (2018) 158:None:620	30245394

HDAC2

Tclin

Histone deacetylase 2

3 Activities

Items per page:

1 – 3 of 3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	8.41		J Med Chem, (2020) 63:1:23	31415174

IC50	7.33		Eur J Med Chem, (2019) 183:None:111691	31536895

IC50	7.33		Eur J Med Chem, (2018) 158:None:620	30245394

HDAC6

Tclin

Histone deacetylase 6

2 Activities

Items per page:

1 – 2 of 2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	8.04		MedChemComm, (2019) 10:4:538

IC50	6.1		J Med Chem, (2020) 63:1:23	31415174

HDAC4

Tclin

Histone deacetylase 4

1 Activities

Items per page:

1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	6.29		Eur J Med Chem, (2018) 158:None:620	30245394