ripasudil
Rho-associated kinase inhibitor for the treatment of glaucoma and ocular hypertension
Ligand Summary
UNII: 11978226XX
PubChem: 11625386
PubChem: 9863672
ChEMBL: CHEMBL4594454
ChEMBL: CHEMBL3426621
DrugCentral: 4938
LyCHI: 6CRF1W92FPCB
Target Activities
ROCK2
Rho-associated protein kinase 2
4 Activities
Items per page:
1 – 4 of 4
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 8.42 | J. Med. Chem., (2015) 58:10:4309 | ||||
IC50 | 7.72 | J. Med. Chem., (2016) 59:3:788 | ||||
IC50 | 7.72 | J Med Chem, (2020) 63:18:10135 | ||||
IC50 | 7.72 | INHIBITOR | ||||
ROCK1
Rho-associated protein kinase 1
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 7.29 | INHIBITOR | ||||