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retigabine

Ligand Summary
Ligand Structure
Rendered image for the query structure
Description
In vitro studies indicate that ezogabine enhances transmembrane potassium currents mediated by the KCNQ (Kv7.2 to 7.5) family of ion channels. By activating KCNQ channels, ezogabine is thought to stabilize the resting membrane potential and reduce brain excitability.
Synonyms & Links
Guide to Pharmacology: 2601
DrugCentral: 4181
LyCHI:  FRQZ6WHCCCQN


Target Activities