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quinidine

Ligand Summary
Ligand Structure
Rendered image for the query structure
Description
An optical isomer of quinine, extracted from the bark of the CHINCHONA tree and similar plant species. This alkaloid dampens the excitability of cardiac and skeletal muscles by blocking sodium and potassium currents across cellular membranes. It prolongs cellular ACTION POTENTIALS, and decreases automaticity. Quinidine also blocks muscarinic and alpha-adrenergic neurotransmission.
Synonyms & Links
Guide to Pharmacology: 2342
DrugCentral: 2346
LyCHI:  TTP6PN9UM1K1


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Target Activities