primidone
A barbiturate derivative that acts as a GABA modulator and anti-epileptic agent. It is partly metabolized to PHENOBARBITAL in the body and owes some of its actions to this metabolite.
Ligand Summary
UNII: 13AFD7670Q
PubChem: 4909
Guide to Pharmacology: 5338
ChEMBL: CHEMBL856
DrugCentral: 2267
LyCHI: 8YMDC812PJGZ
Target Activities
TRPM3
Transient receptor potential cation channel subfamily M member 3
2 Activities
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1 – 2 of 2
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
- | 6.2 | |||||
IC50 | 6.2 | BLOCKER | ||||
GABRA1
Gamma-aminobutyric acid receptor subunit alpha-1
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
POSITIVE ALLOSTERIC MODULATOR | ||||||
GABRG2
Gamma-aminobutyric acid receptor subunit gamma-2
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
POSITIVE ALLOSTERIC MODULATOR | ||||||
GABRB2
Gamma-aminobutyric acid receptor subunit beta-2
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
POSITIVE ALLOSTERIC MODULATOR | ||||||