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ponesimod

Ligand Summary
Ligand Structure
Rendered image for the query structure
Description
Ponesimod is a sphingosine 1-phosphate (S1P) receptor 1 modulator that binds with high affinity to S1P receptor 1. Ponesimod blocks the capacity of lymphocytes to egress from lymph nodes, reducing the number of lymphocytes in peripheral blood. The mechanism by which ponesimod exerts therapeutic effects in multiple sclerosis is unknown, but may involve reduction of lymphocyte migration into the central nervous system
Synonyms & Links
Guide to Pharmacology: 9320
DrugCentral: 5446
LyCHI:  4DVYJN2JZLF5


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Target Activities