phenylbutazone
A butyl-diphenyl-pyrazolidinedione that has anti-inflammatory, antipyretic, and analgesic activities. It has been used in ANKYLOSING SPONDYLITIS; RHEUMATOID ARTHRITIS; and REACTIVE ARTHRITIS.
Ligand Summary
UNII: GN5P7K3T8S
PubChem: 4781
Guide to Pharmacology: 7270
ChEMBL: CHEMBL101
DrugCentral: 2145
LyCHI: LL6B7PDX34DR
Target Activities
NAPRT
Nicotinate phosphoribosyltransferase
3 Activities
Items per page:
1 – 3 of 3
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Ki | 10 | None, None:None:None | ||||
Ki | 10 | |||||
Ki | 10 | |||||
PTGS1
Prostaglandin G/H synthase 1
2 Activities
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1 – 2 of 2
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 5.52 | |||||
IC50 | 5.52 | INHIBITOR | ||||
PTGS2
Prostaglandin G/H synthase 2
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 3.55 | |||||