phencyclidine
A hallucinogen formerly used as a veterinary anesthetic, and briefly as a general anesthetic for humans. Phencyclidine is similar to KETAMINE in structure and in many of its effects. Like ketamine, it can produce a dissociative state. It exerts its pharmacological action through inhibition of NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE). As a drug of abuse, it is known as PCP and Angel Dust.
Ligand Summary
UNII: J1DOI7UV76
PubChem: 6468
Guide to Pharmacology: 4282
ChEMBL: CHEMBL275528
DrugCentral: 2121
LyCHI: ZFS4CBHZQX9A
Target Activities
PRCP
Lysosomal Pro-X carboxypeptidase
3 Activities
Items per page:
1 – 3 of 3
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 7.04 | J. Med. Chem., (1998) 41:4:468 | ||||
IC50 | 7.04 | J. Med. Chem., (1989) 32:6:1242 | ||||
IC50 | 7.04 | |||||
SIGMAR1
Sigma non-opioid intracellular receptor 1
3 Activities
GRIN2C
Glutamate receptor ionotropic, NMDA 2C
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 7.11000013 | |||||