pegaptanib
Ligand Summary
a pegylated modified oligonucleotide that binds with high specificity and affinity to extracellular Vascular Endothelial Growth Factor (VEGF165) inhibiting its activity, VEGF is a secreted protein that induces angiogenesis, vascular permeability and inflammation, all of which are thought to contribute to the progression of the neovascular (wet) form of AMD
ChEMBL: CHEMBL2108752
DrugCentral: 4905
LyCHI: pegaptanib
Target Activities
1 Activities
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