pegaptanib
a pegylated modified oligonucleotide that binds with high specificity and affinity to extracellular Vascular Endothelial Growth Factor (VEGF165) inhibiting its activity, VEGF is a secreted protein that induces angiogenesis, vascular permeability and inflammation, all of which are thought to contribute to the progression of the neovascular (wet) form of AMD
Ligand Summary
Target Activities
VEGFA
Vascular endothelial growth factor A
1 Activities
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ANTAGONIST | ||||||