patisiran
Ligand Summary
Patisiran is a double-stranded siRNA that causes degradation of mutant and wild-type TTR mRNA through RNA interference, which results in a reduction of serum TTR protein and TTR protein deposits in tissues.
ChEMBL: CHEMBL3989987
DrugCentral: 5313
LyCHI: patisiran
Target Activities
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
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ANTISENSE INHIBITOR | ||||||