oxybutynin
Ligand Summary
Oxybutynin acts as a competitive antagonist of acetylcholine at post-ganglionic muscarinic receptors, resulting in relaxation of bladder smooth muscle. Oxybutynin is a racemic (50:50) mixture of R- and S-isomers. Antimuscarinic activity resides predominantly in the R-isomer. The R-isomer of oxybutynin shows greater selectivity for the M1 and M3 muscarinic subtypes (predominant in bladder detrusor muscle and parotid gland) compared to the M2 subtype (predominant in cardiac tissue).
UNII: K9P6MC7092
PubChem: 4634
Guide to Pharmacology: 359
ChEMBL: CHEMBL1231
DrugCentral: 2028
LyCHI: C5THXP9M3HZH
Target Activities
33 Activities
Items per page:
1 – 10 of 33
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